SCHEMBL9225516

SCHEMBL9225516

NC(N)(CCCC(=O)O)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
EPHX2 P34913 1/20 0.40
EPHX1 P07099 1/20 0.38
KDM5A P29375 3/20 0.36
PHF8 Q9UPP1 3/20 0.36
KDM2A Q9Y2K7 3/20 0.36
KDM4C Q9H3R0 2/20 0.36
KDM4A O75164 1/20 0.36
CYP1A2 P05177 2/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 5/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
TSHR P16473 3/20 0.35
THRB P10828 2/20 0.35
BLM P54132 2/20 0.35
KMT2A Q03164 2/20 0.35
GABRR3 A8MPY1 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9225076 0.84 ALDH1A1 (0.41) ALDH1A1EPHX2EPHX1KDM5APHF8
Adipic Acid SCHEMBL10598846 0.81 ALDH1A1 (0.44) ALDH1A1EPHX2EPHX1KDM5APHF8
SCHEMBL11751802 0.78 ALDH1A1 (0.42) ALDH1A1EPHX2EPHX1KDM5APHF8
SCHEMBL19148633 0.78 ALDH1A1 (0.42) ALDH1A1EPHX2EPHX1KDM5APHF8
SCHEMBL668614 0.78 ALDH1A1 (0.42) ALDH1A1EPHX2EPHX1KDM5APHF8
SCHEMBL29264079 0.76 ALDH1A1 (0.43) ALDH1A1EPHX2EPHX1KDM5APHF8
SCHEMBL19148632 0.76 ALDH1A1 (0.39) ALDH1A1EPHX2EPHX1KDM5APHF8
SCHEMBL8745903 0.76 ALDH1A1 (0.39) ALDH1A1EPHX2EPHX1KDM5APHF8
SCHEMBL11323557 0.75 ALDH1A1 (0.40) ALDH1A1EPHX2EPHX1KDM5APHF8
Hydrochloric Acid SCHEMBL8745885 0.74 ALDH1A1 (0.38) ALDH1A1EPHX2EPHX1KDM5APHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5378691-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-01-03 US disclosed
US-5215967-A AMINOACID DERIVATIVES INHIBITING RENIN MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-06-01 US disclosed
CN-1037155-A Amino acid derivative MERCK PATENT GMBH (DE) 1989-11-15 CN disclosed
US-4746649-A Diamino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1988-05-24 US disclosed