Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 3/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8745885 | 0.98 | ALDH1A1 (0.38) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL9225076 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL6282896 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNAEPHX2KEAP1NFE2L2 | |
| SCHEMBL8745889 | 0.77 | ALDH1A1 (0.39) | ALDH1A1THRBLMNAKDM5APHF8 | |
| SCHEMBL10355082 | 0.77 | KEAP1 (0.38) | KEAP1NFE2L2GRM2GRM3KIF11 | |
| SCHEMBL9225516 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL16670669 | 0.75 | ALDH1A1 (0.35) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL7297962 | 0.75 | LMNA (0.37) | ALDH1A1MEN1KMT2ALMNAEPHX2 | |
| SCHEMBL19150278 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL19148259 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MEN1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519763-B1 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO PERFUMERY CO LTD (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5502221-A | HYPOTENSIVE INTERMEDIATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5442105-A | Catalytic hydrogenation, epoxidation, reacting product with trialkylsilyl azide in the presence of a Lewis acid, hydrogenolysis | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0519763-A2 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-5166400-A | Intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates | PFIZER INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5036155-A | Process for isopropyl 3S-amino-2R-hydroxy-alkanoates | PFIZER INC. (US) | 1991-07-30 | — | — | US | disclosed |
| US-4965372-A | Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates | PFIZER INC. (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0379288-A1 | Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates | PFIZER INC. (US) | 1990-07-25 | — | — | EP | disclosed |