Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556804 | 0.91 | REN (0.41) | REN | |
| SCHEMBL7298963 | 0.91 | REN (0.41) | REN | |
| SCHEMBL9556796 | 0.91 | REN (0.41) | REN | |
| SCHEMBL7302831 | 0.91 | REN (0.41) | REN | |
| SCHEMBL7289817 | 0.91 | REN (0.41) | REN | |
| SCHEMBL7283971 | 0.90 | REN (0.42) | REN | |
| SCHEMBL7282601 | 0.90 | REN (0.42) | REN | |
| SCHEMBL10510052 | 0.87 | REN (0.42) | REN | |
| SCHEMBL9554910 | 0.87 | REN (0.42) | REN | |
| SCHEMBL7290037 | 0.86 | REN (0.40) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389616-A | Renin inhibitor, hypotensive agent | HOFFMAN-LAROCHE INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5256645-A | Renin inhibitors; hypotensive agents | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5134123-A | Renin enzyme inhibitors for cardiovascular disorders and high blood pressure | HOFFMAN-LA ROCHE INC. (US) | 1992-07-28 | — | — | US | disclosed |