Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225762 | 0.81 | ESR1 (0.42) | MAPTESR1ESR2ALDH1A1TSHR | |
| SCHEMBL4194599 | 0.78 | HDAC3 (0.36) | MAPTESR1ESR2 | |
| SCHEMBL10611414 | 0.78 | MAOA (0.40) | ESR1ESR2 | |
| SCHEMBL28330067 | 0.78 | KCNH2 (0.41) | ALDH1A1TSHR | |
| SCHEMBL3238058 | 0.78 | ESR1 (0.34) | MAPTESR1ESR2 | |
| SCHEMBL4660213 | 0.78 | NR1H2 (0.40) | MAPTTDP1ESR1ESR2TSHR | |
| SCHEMBL11408724 | 0.77 | TDP1 (0.37) | TDP1TRPA1ALDH1A1TSHR | |
| SCHEMBL8986065 | 0.77 | TDP1 (0.37) | TDP1TRPA1ALDH1A1TSHR | |
| SCHEMBL4908749 | 0.77 | ESR1 (0.33) | MAPTESR1ESR2 | |
| SCHEMBL11362309 | 0.77 | ESR1 (0.38) | MAPTTDP1ESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167617-A | Rapidly curable siloxane composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1979-09-11 | — | — | US | disclosed |
| US-4139403-A | Dinitroalkyl and fluorodinitroalkyl silicon compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1979-02-13 | — | — | US | disclosed |