Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219072 | 0.80 | FDPS (0.47) | KCNA5CYP19A1CYP3A4FDPSBTN3A1 | |
| SCHEMBL8711994 | 0.73 | FDPS (0.49) | CYP3A4FDPSBTN3A1PDE3ALMNA | |
| SCHEMBL6777285 | 0.71 | LMNA (0.43) | KCNA5CYP19A1CYP3A4FDPSLMNA | |
| Lithium SCHEMBL8712004 | 0.71 | FDPS (0.49) | CYP3A4FDPSBTN3A1PDE3ALMNA | |
| Lithium Ion SCHEMBL8711998 | 0.68 | FDPS (0.48) | CYP3A4FDPSBTN3A1PDE3ALMNA | |
| SCHEMBL15533205 | 0.67 | FDPS (0.53) | KCNA5CYP19A1CYP3A4FDPSBTN3A1 | |
| SCHEMBL9224803 | 0.67 | POLB (0.43) | KCNA5LMNASMN1; SMN2NAPRT | |
| SCHEMBL4725467 | 0.66 | FDPS (0.51) | KCNA5CYP19A1CYP3A4FDPSBTN3A1 | |
| Sulfuric Acid SCHEMBL11701746 | 0.65 | CNR1 (0.49) | KCNA5CYP19A1LMNATDP1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL11698108 | 0.65 | CNR1 (0.49) | KCNA5CYP19A1LMNATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642518-A1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024495-A1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |