Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204786 | 0.83 | LMNA (0.64) | SMN1; SMN2LMNAKDM4EPDE10AHPGD | |
| SCHEMBL4165094 | 0.79 | SMN1; SMN2 (0.68) | TDO2SMN1; SMN2LMNAKDM4EPDE10A | |
| SCHEMBL247426 | 0.77 | LMNA (0.51) | SMN1; SMN2LMNAKDM4EPDE10AHPGD | |
| SCHEMBL10864298 | 0.77 | LMNA (0.52) | SMN1; SMN2LMNAKDM4EPDE10AHPGD | |
| SCHEMBL9225854 | 0.76 | KDM4E (0.68) | SMN1; SMN2LMNAKDM4EPDE10ANQO2 | |
| Biphenyl SCHEMBL8212316 | 0.75 | ALDH1A1 (0.57) | KDM4EHPGDALDH1A1RAB9AMEN1 | |
| SCHEMBL9409728 | 0.75 | PARP1 (0.48) | SMN1; SMN2KDM4EPDE10AALDH1A1RAB9A | |
| SCHEMBL5538855 | 0.75 | LMNA (0.50) | SMN1; SMN2LMNAKDM4EPDE10AHPGD | |
| Naphthalene SCHEMBL1132213 | 0.74 | HSD17B10 (0.55) | SMN1; SMN2KDM4EHPGDALDH1A1RAB9A | |
| SCHEMBL4175720 | 0.74 | LMNA (0.42) | TDO2SMN1; SMN2LMNAKDM4EPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639570-A1 | Process for the preparation of aromatic carboxylic acids | BASF Aktiengesellschaft (DE) | 1995-02-22 | — | — | EP | disclosed |