Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 16/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SHBG | P04278 | 2/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226234 | 1.00 | SRD5A2 (0.68) | SRD5A2CYP19A1LMNASHBGSERPINA6 | |
| SCHEMBL21140787 | 0.89 | SRD5A2 (0.69) | SRD5A2CYP19A1LMNASHBGSERPINA6 | |
| SCHEMBL17831186 | 0.89 | SRD5A2 (0.63) | SRD5A2CYP19A1 | |
| SCHEMBL15079264 | 0.89 | SRD5A2 (0.63) | SRD5A2CYP19A1 | |
| SCHEMBL2909333 | 0.89 | SRD5A2 (0.69) | SRD5A2CYP19A1LMNASHBGSERPINA6 | |
| SCHEMBL6379452 | 0.89 | SRD5A2 (0.63) | SRD5A2CYP19A1 | |
| SCHEMBL17591557 | 0.89 | SRD5A2 (0.63) | SRD5A2CYP19A1 | |
| SCHEMBL17562405 | 0.85 | SRD5A2 (0.71) | SRD5A2CYP19A1LMNASHBGSERPINA6 | |
| SCHEMBL16387357 | 0.85 | SRD5A2 (0.71) | SRD5A2CYP19A1LMNASHBGSERPINA6 | |
| SCHEMBL11517545 | 0.84 | SRD5A2 (0.73) | SRD5A2CYP19A1LMNASHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438134-A | Endocrine disorders, reproductive control | JENAPHARM GMBH (DE) | 1995-08-01 | — | — | US | disclosed |
| EP-0538348-A1 | PROCESS FOR PRODUCING UNSATURATED 17-ALPHA-CYANOMETHYL-17-BETA-HYDROXYSTEROIDS. | JENAPHARM GMBH (DE) | 1993-04-28 | — | — | EP | disclosed |
| US-4720357-A | New process for manufacturing derivatives of 17 alpha-hydroxy 19-nor progesterone and novel intermediates for use therein | LABORATOIRE THERAMEX (MC) | 1988-01-19 | — | — | US | disclosed |
| EP-0124934-B1 | 17-(ISOCYANO-SULFONYLMETHYLENE)-STEROIDS, 17-(FORMAMIDO-SULFONYLMETHYLENE)-STEROIDS AND THEIR PREPARATION | GIST-BROCADES N.V. (NL) | 1986-11-20 | — | — | EP | disclosed |
| EP-0124934-A1 | 17-(Isocyano-sulfonylmethylene)-steroids, 17-(formamido-sulfonylmethylene)-steroids and their preparation | GIST-BROCADES N.V. (NL) | 1984-11-14 | — | — | EP | disclosed |
| EP-0123734-A1 | 17-(Isocyano-sulfonylmethylene)-steroids, 17-(formamido-sulfonylmethylene)-steroids and their preparation | GIST-BROCADES N.V. (NL) | 1984-11-07 | — | — | EP | disclosed |