Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242287 | 0.88 | KCNA5 (0.66) | HIF1AMEN1KMT2AMAPTRAB9A | |
| SCHEMBL27953140 | 0.81 | NPC1 (0.77) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL28559896 | 0.80 | KMT2A (0.63) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL6141162 | 0.80 | HTT (0.53) | HIF1AKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25148983 | 0.79 | CYP2C9 (0.65) | HIF1AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14830351 | 0.79 | HIF1A (0.81) | HIF1ARAB9ASMN1; SMN2HTTTSHR | |
| SCHEMBL28912557 | 0.78 | MEN1 (1.00) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL2652549 | 0.77 | HTT (0.53) | HIF1AKMT2APOLBCFDHTT | |
| SCHEMBL9848860 | 0.77 | HTT (0.57) | HIF1AKMT2AHTTHPGDTSHR | |
| SCHEMBL12700344 | 0.77 | HTT (0.76) | HIF1AKMT2AMAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667342-A1 | Substituted Arylureas and their use as anti-atheriosclerotic compounds | BAYER AG (DE) | 1995-08-16 | — | — | EP | disclosed |