Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.81 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494091 | 0.88 | HIF1A (0.66) | HIF1ANOX4FOLH1ALDH1A1KDM4C | |
| SCHEMBL28741561 | 0.84 | HIF1A (0.61) | HIF1ANOX4ALDH1A1TSHRFFAR1 | |
| SCHEMBL6119714 | 0.84 | HIF1A (0.61) | HIF1ANOX4ALDH1A1KDM4CHTT | |
| SCHEMBL9567555 | 0.83 | HPGD (0.63) | HIF1AFOLH1ALDH1A1KDM4CRAB9A | |
| SCHEMBL28216256 | 0.82 | HIF1A (0.83) | HIF1ANOX4ALDH1A1ALOX15TSHR | |
| SCHEMBL30879601 | 0.82 | HIF1A (0.57) | HIF1AFOLH1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL29022251 | 0.80 | HIF1A (0.59) | HIF1ANOX4ALDH1A1RAB9AGFER | |
| SCHEMBL9226506 | 0.79 | HIF1A (0.72) | HIF1AALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10055008 | 0.79 | MAPT (0.53) | HIF1AALDH1A1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL22634084 | 0.78 | HIF1A (0.54) | HIF1AFOLH1ALDH1A1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10825992-B2 | Spirobifluorene compounds for light emitting devices | SUMITOMO CHEMICAL CO., LTD (JP) | 2020-11-03 | — | — | US | disclosed |
| EP-2760846-B1 | SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES | SUMITOMO CHEMICAL CO (JP) | 2017-04-26 | — | — | EP | disclosed |
| US-20140326979-A1 | SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES | SUMITOMO CHEMICAL CO., LTD (JP) | 2014-11-06 | — | — | US | disclosed |
| US-20140231713-A1 | SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES | SUMITOMO CHEMICAL CO., LTD (JP) | 2014-08-21 | — | — | US | disclosed |
| EP-2760847-A1 | SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES | Solvay SA (BE) | 2014-08-06 | — | — | EP | disclosed |
| EP-2760846-A1 | SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES | Solvay SA (BE) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013045410-A1 | SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES | SOLVAY SA (BE) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013045411-A1 | SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES | SOLVAY SA (BE) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10825992-B2 | Spirobifluorene compounds for light emitting devices | CRY1, TRPA1, ALDH1A2 | HIF1A 4704/4885NOX4 1007/4885FOLH1 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.