Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250 | 0.88 | PNP (0.66) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL3308563 | 0.87 | PNP (0.51) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL1262627 | 0.87 | PNP (0.51) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL1980960 | 0.87 | PNP (0.64) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL3310277 | 0.86 | PNP (0.50) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL3021043 | 0.86 | PNP (0.50) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL1533551 | 0.86 | MPO (0.54) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL3303816 | 0.86 | KDM4E (0.51) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL9231918 | 0.85 | PNP (0.50) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL9235123 | 0.85 | PNP (0.47) | PNPADORA3ADORA2BPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7258255-A | — | — | None | — | — | JP | disclosed |
| JP-H07258255-A | BENZYLGUANINE DERIVATIVE | TOAGOSEI CO LTD | 1995-10-09 | — | — | JP | disclosed |