Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 7/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250 | 0.99 | PNP (0.66) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL22631570 | 0.89 | PNP (0.55) | PNPADORA3ADORA2BPDE4APDE4B | |
| Hydrochloric Acid SCHEMBL17186506 | 0.87 | PNP (0.53) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL9226992 | 0.87 | PNP (0.51) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL1262627 | 0.87 | PNP (0.51) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL3308563 | 0.87 | PNP (0.51) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL6268535 | 0.86 | ADORA3 (0.60) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL3303816 | 0.86 | KDM4E (0.51) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL1533551 | 0.86 | MPO (0.54) | PNPADORA3ADORA2BPDE4APDE4B | |
| SCHEMBL3021043 | 0.86 | PNP (0.50) | PNPADORA3ADORA2BPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2329272-B1 | METHOD FOR DETECTING MEMBRANE PROTEIN INTERNALIZATION | ION BEAM APPLIC (BE) | 2013-10-09 | — | — | EP | disclosed |
| EP-2329272-A2 | METHOD FOR DETECTING MEMBRANE PROTEIN INTERNALIZATION | Cis-Bio International (FR) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010012962-A2 | METHOD FOR DETECTING MEMBRANE PROTEIN INTERNALIZATION | CIS-BIO INTERNATIONAL (FR) | 2010-02-04 | — | — | WO | disclosed |