Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543767 | 0.85 | TDP1 (0.50) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL11981379 | 0.85 | TDP1 (0.50) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL28173166 | 0.85 | KMT2A (0.63) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL12330692 | 0.79 | TDP1 (0.44) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL9406767 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL27961733 | 0.79 | RAD52 (0.48) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL9385710 | 0.79 | GAA (0.51) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL9406598 | 0.79 | TLR8 (0.57) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL22597831 | 0.75 | TDP1 (0.52) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL15624645 | 0.75 | TDP1 (0.47) | ALDH1A1KMT2AKDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003433-A1 | BIOLOGICAL APPLICATIONS OF ALKALOIDS DERIVED FROM THE TUNICATE EUDISTOMA sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-17 | — | — | WO | claimed |
| US-5432172-A | Biological applications of alkaloids derived from the tunicate Eudistoma sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1995-07-11 | — | — | US | disclosed |
| EP-0328535-B1 | THE ADMINISTRATION OF MONOAMINE ACRIDINES IN CHOLINERGIC NEURONAL DEFICIT STATES | SUMMERS WILLIAM KOOPMANS (US) | 1994-06-01 | — | — | EP | disclosed |
| EP-0595365-A1 | Pharmaceutical composition for the treatment of underlying nonpharmacologically induced nervous system cholinergic deficit state comprising monoamine acridine derivatives | Summers, William Koopmans (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1994003433-A1 | BIOLOGICAL APPLICATIONS OF ALKALOIDS DERIVED FROM THE TUNICATE EUDISTOMA sp. | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-17 | — | — | WO | disclosed |
| US-5278168-A | Biological applications of alkaloids derived from the tunicate Eudistoma sp. | THE RESEARCH FOUNDATION OF STATE UNIVERISTY OF NEW YORK (US) | 1994-01-11 | — | — | US | disclosed |
| US-4816456-A | Administration of monoamine acridines in cholinergic neuronal deficit states | SUMMERS WILLIAM K (US) | 1989-03-28 | — | — | US | disclosed |