Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.56 |
| ▸ | ABCC9 | O60706 | 9/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223478 | 0.87 | ABCB1 (0.59) | ABCB1ABCC9 | |
| SCHEMBL9224765 | 0.85 | ABCB1 (0.57) | ABCB1ABCC9 | |
| SCHEMBL9223921 | 0.84 | ABCB1 (0.61) | ABCB1ABCC9 | |
| SCHEMBL9221558 | 0.80 | ABCB1 (0.56) | ABCB1ABCC9 | |
| SCHEMBL9224832 | 0.79 | ABCC8 (0.53) | ABCB1ABCC9 | |
| SCHEMBL9224892 | 0.79 | ABCC8 (0.53) | ABCB1ABCC9 | |
| SCHEMBL9231522 | 0.79 | ABCB1 (0.57) | ABCB1ABCC9 | |
| SCHEMBL9230006 | 0.79 | ABCC9 (0.53) | ABCB1ABCC9 | |
| SCHEMBL9223744 | 0.78 | ABCB1 (0.54) | ABCB1ABCC9 | |
| SCHEMBL4841296 | 0.78 | ABCB1 (0.52) | ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648758-A1 | 4-Arylamino-benzopyran and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-04-19 | — | — | EP | disclosed |