Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12889529 | 0.91 | ALOX5AP (0.45) | ALOX5APFEN1PDE2ACTSKNAAA | |
| SCHEMBL12889521 | 0.90 | PDE2A (0.45) | ALOX5APFEN1PDE2ACTSKNAAA | |
| SCHEMBL9228675 | 0.85 | APP (0.46) | ALOX5APFEN1PDE2ACTSKNAAA | |
| SCHEMBL9226902 | 0.84 | GPR3 (0.48) | ALOX5APFEN1PDE3BPDE3AGRM2 | |
| SCHEMBL9225120 | 0.84 | GRM2 (0.43) | ALOX5APFEN1PDE2ACTSKNAAA | |
| SCHEMBL14899961 | 0.84 | ALOX5AP (0.41) | ALOX5APFEN1PDE2ACTSKNAAA | |
| SCHEMBL20380739 | 0.83 | CTSK (0.35) | ALOX5APFEN1PDE2ACTSKNAAA | |
| SCHEMBL12624776 | 0.83 | ALOX5AP (0.42) | ALOX5APFEN1PDE2ACTSKNAAA | |
| SCHEMBL12625536 | 0.83 | ALOX5AP (0.42) | ALOX5APFEN1PDE2ACTSKNAAA | |
| SCHEMBL9228814 | 0.81 | ALOX5AP (0.43) | ALOX5APFEN1CTSKNAAAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-B1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK PATENT GMBH (DE) | 1995-12-20 | — | — | EP | disclosed |
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |