Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 11/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228887 | 1.00 | SLC29A1 (0.77) | SLC29A1TP53CYP3A4HIF1AABCC4 | |
| SCHEMBL3895881 | 0.87 | SLC29A1 (1.00) | SLC29A1TP53 | |
| SCHEMBL20626431 | 0.87 | SLC29A1 (1.00) | SLC29A1TP53 | |
| SCHEMBL638749 | 0.87 | SLC29A1 (1.00) | SLC29A1TP53 | |
| SCHEMBL14713263 | 0.87 | SLC29A1 (1.00) | SLC29A1TP53 | |
| SCHEMBL638750 | 0.87 | SLC29A1 (1.00) | SLC29A1TP53 | |
| SCHEMBL8819317 | 0.87 | ADORA3 (0.74) | SLC29A1TP53CYP3A4HIF1A | |
| SCHEMBL8819300 | 0.87 | ADORA3 (0.74) | SLC29A1TP53CYP3A4HIF1A | |
| SCHEMBL10684662 | 0.82 | SLC29A1 (0.78) | SLC29A1TP53CYP3A4HIF1AABCC4 | |
| SCHEMBL10684673 | 0.82 | SLC29A1 (0.78) | SLC29A1TP53CYP3A4HIF1AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607367-A1 | NOVEL ADENOSINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-07-27 | — | — | EP | claimed |
| WO-1993023417-A1 | NOVEL ADENOSINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | claimed |
| US-5430027-A | 2-chloro-N6 -substituted adenosines, their pharmaceutical compositions, and activity in treating ischemias | NOVO NORDISK A/S (DK) | 1995-07-04 | — | — | US | disclosed |