Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.77 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.63 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684673 | 1.00 | SLC29A1 (0.78) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL638749 | 0.88 | SLC29A1 (1.00) | SLC29A1ADORA3TP53 | |
| SCHEMBL20626431 | 0.88 | SLC29A1 (1.00) | SLC29A1ADORA3TP53 | |
| SCHEMBL14713263 | 0.88 | SLC29A1 (1.00) | SLC29A1ADORA3TP53 | |
| SCHEMBL3895881 | 0.88 | SLC29A1 (1.00) | SLC29A1ADORA3TP53 | |
| SCHEMBL638750 | 0.88 | SLC29A1 (1.00) | SLC29A1ADORA3TP53 | |
| SCHEMBL6852552 | 0.87 | ADORA3 (1.00) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6852543 | 0.87 | ADORA3 (1.00) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL12580130 | 0.87 | PRKAG1 (0.74) | SLC29A1ADORA3ADORA2ATP53CYP3A4 | |
| SCHEMBL20626366 | 0.87 | PRKAG1 (0.74) | SLC29A1ADORA3ADORA2ATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251339-A2 | N6- substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same | WARNER-LAMBERT COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |