Phthalimide

Phthalimide

SCHEMBL9229

O=C1NC(=O)c2ccccc21.[KH]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.94
CASP7 P55210 3/20 0.75
CASP3 P42574 2/20 0.75
CASP6 P55212 2/20 0.75
CASP8 Q14790 2/20 0.75
CASP2 P42575 1/20 0.75
PARP1 P09874 3/20 0.56
PDGFRA P16234 1/20 0.56
FER P16591 1/20 0.56
LTK P29376 1/20 0.56
CDK8 P49336 1/20 0.56
ACVR1 Q04771 1/20 0.56
LRRK2 Q5S007 1/20 0.56
DYRK1B Q9Y463 1/20 0.56
LMNA P02545 3/20 0.52
MAPK1 P28482 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
HSD17B10 Q99714 1/20 0.52
MAOA P21397 5/20 0.50
MAOB P27338 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL1205291 1.00 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10592849 0.97 GSK3B (0.88) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10192661 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL30125197 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL28226707 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL7771670 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL29366030 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL11040503 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL64 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL28074926 0.94 GSK3B (0.83) GSK3BCASP7CASP3CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11165 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010725-A Method for preparing DOTP from waste PET 中国科学院青岛生物能源与过程研究所 2026-05-12 CN claimed
EP-3560932-B1 PROCESS FOR PREPARING 7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES OF SAME JAPAN TOBACCO INC (JP) 2026-03-11 EP claimed
US-20250223717-A1 COPPER PLATING ADDITIVE COMPOSITIONS, COPPER PLATING SOLUTIONS, AND USES THEREOF JIANGYIN NANOPORE INNOVATIVE MATERIALS TECHNOLOGY LTD (CN) 2025-07-10 US claimed
EP-4430102-B1 POLYOXAZOLINE BASED THERMAL LATENT CURING AGENTS FOR THERMOSET RESINS UNIV SABANCI (TR) 2025-06-25 EP claimed
CN-120082177-A Matte antistatic elastomer cable material and preparation method thereof 江苏秀浦利欧科技有限公司 2025-06-03 CN claimed
CN-119874769-A Preparation method of glufosinate ammonium salt 湖南化工研究院有限公司 2025-04-25 CN claimed
CN-119798218-A E3 enzyme ligand-connecting chain complex and preparation method thereof 南京优氟医药科技有限公司 2025-04-11 CN claimed
CN-119798183-A Preparation method of oxazole compound 上海药坦药物研究开发有限公司 2025-04-11 CN claimed
US-20250115585-A1 METHOD FOR PRODUCING DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-10 US claimed
CN-119751283-A Method for preparing 5-aminolevulinic acid step by step under assistance of ultrasound 昆明理工大学 2025-04-04 CN claimed
CN-86105088-A Preparation is together with-dihalo-and four halos-1,12-diamino-4, the method for 9-diaza-dodecane 1987-04-29 CN claimed
CN-86105154-A Together with-dihalo-1, the preparation method of 8-diamino-4-azepine-octane 1987-04-22 CN claimed
EP-0215319-A2 Gem-dihalo-1,8-diamino-4-aza-octanes MERRELL DOW PHARMACEUTICALS INC. (US) 1987-03-25 EP claimed
CN-85100231-A Synthesizing polyglycoldiamine by sealed method 1986-10-08 CN claimed
CN-85100260-A Synthesis of polyglycoldiamine 1986-07-09 CN claimed
EP-0086454-A1 Preparation of trans-zeatin intermediate J.T. Baker Chemical Co. (US) 1983-08-24 EP claimed
US-4373071-A RESIN SUPPORTS; GENETIC ENGINEERING CITY OF HOPE RESEARCH INSTITUTE (US) 1983-02-08 US claimed
US-4154727-A REACTING A GLYCINAMIDE WITH A HALOACETYL HALIDE SHIONOGI & CO., LTD. (JP) 1979-05-15 US claimed
US-4087439-A New high melting N,N'-terephthaloyl bis-phthalimide and its use as an ester interlinking agent for polyesters THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-05-02 US claimed
US-4082766-A CHLORINATION OF ALKALI METAL SALT OF PHTHALIMIDE ELI LILLY AND COMPANY (US) 1978-04-04 US claimed