SCHEMBL922916

SCHEMBL922916

COCc1ccc(C(=O)NCc2ccc(Oc3ccc(C(F)(F)F)cc3F)cc2)c(N)n1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 15/20 0.50
PPARG P37231 11/20 0.50
PPARD Q03181 11/20 0.50
RECQL P46063 1/20 0.44
KCNQ3 O43525 1/20 0.43
KCNQ2 O43526 1/20 0.43
MAPK14 Q16539 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922608 0.93 PPARA (0.46) PPARAPPARGPPARDRECQLKCNQ3
SCHEMBL921805 0.90 PPARD (0.43) PPARAPPARGPPARDMAPK14
SCHEMBL920005 0.89 MAPK14 (0.53) PPARAPPARGPPARDRECQLMAPK14
SCHEMBL920403 0.88 PPARA (0.53) PPARAPPARGPPARDKCNQ3KCNQ2
SCHEMBL921739 0.87 PPARA (0.50) PPARAPPARGPPARDKCNQ3KCNQ2
SCHEMBL922456 0.86 PPARD (0.42) PPARAPPARGPPARD
SCHEMBL920726 0.86 RECQL (0.51) PPARAPPARGPPARDRECQLKCNQ3
SCHEMBL920788 0.86 HPGD (0.43) MAPK14
SCHEMBL920422 0.85 PPARA (0.43) PPARAPPARGPPARDRECQLMAPK14
SCHEMBL921950 0.84 PPARD (0.42) PPARAPPARGPPARDMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PPARA 494/4885PPARG 391/4885PPARD 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.