SCHEMBL9229170

SCHEMBL9229170

CCCCCCCc1ccc(-c2ccc(-c3ccc(O[C@H](C)CCCCC)c(F)c3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.53
RARA P10276 2/20 0.53
RARG P13631 1/20 0.53
PDE4A P27815 3/20 0.44
PDE4B Q07343 3/20 0.44
PDE4C Q08493 3/20 0.44
PDE4D Q08499 3/20 0.44
HSD17B10 Q99714 2/20 0.42
TSHR P16473 1/20 0.42
HTR2A P28223 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
MTOR P42345 1/20 0.41
KMT2A Q03164 1/20 0.41
S1PR1 P21453 1/20 0.39
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12036689 1.00 RARB (0.53) RARBRARARARGPDE4APDE4B
SCHEMBL10331188 0.95 RARB (0.47) RARBRARARARGPDE4APDE4B
SCHEMBL6657443 0.93 RARB (0.52) RARBRARARARGPDE4APDE4B
SCHEMBL9628701 0.90 RARB (0.43) RARBRARARARGPDE4APDE4B
SCHEMBL16218456 0.87 MGLL (0.39) RARBRARARARGPDE4APDE4B
SCHEMBL9512597 0.87 RARB (0.49) RARBRARARARGPDE4APDE4B
SCHEMBL6936499 0.86 MGLL (0.43) RARBRARARARGPDE4APDE4B
SCHEMBL9511961 0.86 MGLL (0.43) RARBRARARARGPDE4APDE4B
SCHEMBL9225288 0.86 RARB (0.56) RARBRARARARGHSD17B10TSHR
SCHEMBL9221186 0.86 RARB (0.56) RARBRARARARGHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5382380-A Ferroelectric material for displays KANTO KAGAKU KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed
EP-0360042-B1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU (JP) 1993-11-03 EP disclosed