Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229170 | 0.90 | RARB (0.53) | RARBRARARARGMAPTHTR2A | |
| SCHEMBL12036689 | 0.90 | RARB (0.53) | RARBRARARARGMAPTHTR2A | |
| SCHEMBL6657443 | 0.85 | RARB (0.52) | RARBRARARARGHTR2APDE4A | |
| SCHEMBL10331188 | 0.85 | RARB (0.47) | RARBRARARARGPDE4APDE4B | |
| SCHEMBL9630624 | 0.83 | RAB9A (0.49) | RAB9AMAPTNPC1SMN1; SMN2ATM | |
| SCHEMBL9630649 | 0.83 | RAB9A (0.49) | RAB9AMAPTNPC1SMN1; SMN2ATM | |
| SCHEMBL9840461 | 0.82 | RAB9A (0.43) | RARBRARARAB9AMAPTNPC1 | |
| SCHEMBL9840518 | 0.82 | RAB9A (0.43) | RARBRARARAB9AMAPTNPC1 | |
| SCHEMBL9512597 | 0.78 | RARB (0.49) | RARBRARARARGMAPTSMN1; SMN2 | |
| SCHEMBL16218456 | 0.77 | MGLL (0.39) | RARBRARARARGMAPTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260910-B1 | 3,6-DIPHENYLPYRIDAZINES | Chisso Corporation (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4818430-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1989-04-04 | — | — | US | disclosed |