Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229976 | 0.76 | TYMS (0.52) | LMNAKMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9233968 | 0.76 | POLB (0.49) | LMNAMAPTKMT2AHTTTP53 | |
| SCHEMBL9232599 | 0.76 | LMNA (0.42) | LMNAMAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9780860 | 0.71 | MAPK1 (0.50) | LMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9229979 | 0.70 | CYP1A2 (0.45) | LMNAMAPTKMT2AHTTTP53 | |
| SCHEMBL13433889 | 0.68 | MAPK1 (0.55) | LMNASMN1; SMN2ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL10927242 | 0.68 | ALDH1A1 (0.63) | LMNAMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL811043 | 0.66 | MAPK1 (0.60) | LMNAKMT2ASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL22292430 | 0.66 | ALDH1A1 (0.59) | LMNAMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7628317 | 0.66 | ALDH1A1 (0.59) | LMNAMAPTSMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632040-A1 | Antibacterial imidazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |