Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 5/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093311 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2SLC6A1PTGER4SLC6A9PTGER2 | |
| SCHEMBL9233985 | 0.81 | LTA4H (0.45) | SLC6A1LTA4H | |
| SCHEMBL8718701 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2SLC6A1PTGER4SLC6A9PTGER2 | |
| SCHEMBL9091756 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2SLC6A1PTGER4SLC6A9PTGER2 | |
| SCHEMBL9229546 | 0.75 | GRIN2B (0.34) | SLC6A1 | |
| SCHEMBL9235706 | 0.75 | KMT2A (0.44) | SLC6A1LTA4H | |
| SCHEMBL9091881 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2SLC6A1PTGER4SLC6A9 | |
| SCHEMBL8934441 | 0.73 | NR1I2 (0.43) | LTA4H | |
| SCHEMBL8934439 | 0.71 | NR1I2 (0.44) | LTA4H | |
| SCHEMBL15400625 | 0.70 | PTGER4 (0.64) | SMN1; SMN2SLC6A1PTGER4SLC6A9PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031503-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031503-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |