Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934439 | 0.94 | NR1I2 (0.44) | NR1I2OPRM1DRD3OPRD1LTA4H | |
| SCHEMBL8934341 | 0.81 | LTA4H (0.40) | LTA4HRETEGFRMAPTKMT2A | |
| SCHEMBL9080768 | 0.77 | LTA4H (0.46) | OPRM1LTA4HRETKMT2A | |
| SCHEMBL9233985 | 0.75 | LTA4H (0.45) | LTA4H | |
| SCHEMBL8934348 | 0.75 | SLC6A4 (0.39) | LTA4HRETEGFRMAPTKMT2A | |
| SCHEMBL9230216 | 0.73 | SMN1; SMN2 (0.43) | LTA4H | |
| SCHEMBL8934367 | 0.73 | LTA4H (0.42) | LTA4HRETKMT2A | |
| SCHEMBL9229546 | 0.71 | GRIN2B (0.34) | NR1I2OPRM1DRD3OPRD1 | |
| SCHEMBL8934363 | 0.71 | MTNR1A (0.41) | LTA4HRETKMT2A | |
| SCHEMBL9081168 | 0.71 | HTR2C (0.47) | LTA4HRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031480-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | claimed |