Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12233621 | 0.85 | NFKB1 (0.42) | ALDH1A1LMNAMAPTKDM4EGAA | |
| SCHEMBL9229135 | 0.82 | MAPT (0.36) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL2785039 | 0.81 | TYR (0.41) | ALDH1A1LMNAMAPTKDM4EGAA | |
| SCHEMBL9228146 | 0.80 | ATM (0.35) | ALDH1A1MAPTGAACYP2D6CYP2C9 | |
| SCHEMBL9232619 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTKDM4EGAA | |
| Hydrochloric Acid SCHEMBL9234059 | 0.79 | ATM (0.34) | ALDH1A1MAPTGAACYP2D6CYP2C9 | |
| SCHEMBL9232556 | 0.79 | POLB (0.42) | ALDH1A1LMNAKDM4EGAACYP2C9 | |
| SCHEMBL23057324 | 0.77 | CYP2D6 (0.39) | ALDH1A1LMNAMAPTCYP2D6CYP2C9 | |
| SCHEMBL9228688 | 0.76 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTKDM4EGAA | |
| SCHEMBL9233574 | 0.76 | GAA (0.44) | ALDH1A1LMNAMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666253-A1 | N-t-BUTYLANILINE ANALOG AND LIPID LEVEL DEPRESSANT CONTAINING THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-08-09 | — | — | EP | disclosed |