Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233027 | 0.93 | PPARG (0.45) | PPARGSMN1; SMN2NPC1KMT2AAGTR1 | |
| SCHEMBL9237998 | 0.91 | PPARG (0.43) | PPARGSMN1; SMN2NPC1KMT2A | |
| SCHEMBL9235907 | 0.90 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9231238 | 0.89 | AGTR1 (0.54) | PPARGAGTR1 | |
| SCHEMBL9234723 | 0.86 | PPARG (0.57) | PPARGAGTR1 | |
| SCHEMBL9234703 | 0.86 | PPARG (0.41) | PPARG | |
| SCHEMBL9235240 | 0.84 | PPARG (0.40) | PPARGAGTR1 | |
| SCHEMBL9230412 | 0.84 | PPARG (0.48) | PPARGAGTR1 | |
| SCHEMBL9232948 | 0.83 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9236597 | 0.82 | AGTR1 (0.54) | PPARGAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685467-A1 | NOVEL PYRIMIDINE DERIVATIVE AND MEDICINAL COMPOSITION | NKK CORPORATION (JP) | 1995-12-06 | — | — | EP | disclosed |