Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234703 | 0.92 | PPARG (0.41) | PPARG | |
| SCHEMBL9230386 | 0.91 | PPARG (0.43) | PPARGNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL9237228 | 0.91 | AGTR1 (0.44) | — | |
| SCHEMBL9230511 | 0.89 | AGTR1 (0.52) | PPARG | |
| SCHEMBL8979902 | 0.88 | — | — | |
| SCHEMBL9236476 | 0.87 | PPARG (0.56) | PPARG | |
| SCHEMBL9233027 | 0.86 | PPARG (0.45) | PPARGNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL9234718 | 0.84 | AGTR1 (0.47) | — | |
| SCHEMBL9234122 | 0.83 | AGTR1 (0.43) | — | |
| SCHEMBL9237251 | 0.83 | PPARG (0.45) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685467-A1 | NOVEL PYRIMIDINE DERIVATIVE AND MEDICINAL COMPOSITION | NKK CORPORATION (JP) | 1995-12-06 | — | — | EP | disclosed |