Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229096 | 0.90 | SMN1; SMN2 (0.39) | P2RX7MEN1KMT2ACRHBPHTT | |
| SCHEMBL9082482 | 0.89 | MEN1 (0.41) | MEN1KMT2ACRHBPHTTCRHR2 | |
| Hydrochloric Acid SCHEMBL9080123 | 0.87 | P2RX7 (0.44) | P2RX7MEN1KMT2ACRHBPHTT | |
| SCHEMBL9080758 | 0.87 | P2RX7 (0.38) | P2RX7MEN1KMT2ACRHBPHTT | |
| SCHEMBL9080565 | 0.84 | MEN1 (0.43) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL9079588 | 0.83 | MEN1 (0.43) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL9081325 | 0.83 | GBA1 (0.41) | P2RX7MEN1KMT2ACRHBPHTT | |
| Hydrochloric Acid SCHEMBL9232438 | 0.83 | TYK2 (0.42) | MEN1KMT2ACRHBPHTTCRHR2 | |
| Hydrochloric Acid SCHEMBL9081870 | 0.82 | CRHR1 (0.41) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL9080031 | 0.82 | KMT2A (0.45) | MEN1KMT2ACRHBPHTTCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |