Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 17/20 | 0.66 |
| ▸ | HTR2A | P28223 | 13/20 | 0.66 |
| ▸ | HTR2C | P28335 | 13/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226646 | 0.96 | HTR7 (0.59) | HTR7HTR2AHTR2CHTR1A | |
| Oxalic Acid SCHEMBL9234141 | 0.96 | HTR7 (0.63) | HTR7HTR2AHTR2CHTR1AMAPT | |
| Oxalic Acid SCHEMBL9232306 | 0.92 | HTR7 (0.57) | HTR7HTR2AHTR2CHTR1AMAPT | |
| SCHEMBL9231146 | 0.84 | HTR7 (0.48) | HTR7HTR2AHTR2CHTR1AALDH1A1 | |
| Oxalic Acid SCHEMBL9232791 | 0.81 | ALDH1A1 (0.47) | HTR7HTR2AHTR2CALDH1A1 | |
| Oxalic Acid SCHEMBL9232789 | 0.81 | ALDH1A1 (0.47) | HTR7HTR2AHTR2CALDH1A1 | |
| SCHEMBL9226838 | 0.81 | HTR7 (0.65) | HTR7HTR2AHTR2CHTR1AMAPT | |
| Oxalic Acid SCHEMBL9229197 | 0.79 | HTR7 (0.63) | HTR7HTR2AHTR2CHTR1AMAPT | |
| SCHEMBL5657065 | 0.77 | ALDH1A1 (0.51) | HTR7HTR2AHTR2CHTR1AMAPT | |
| SCHEMBL5658364 | 0.77 | HTR2A (0.58) | HTR7HTR2AHTR2CHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |