Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673543 | 1.00 | TBXAS1 (0.51) | TBXAS1PDE4BAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8843132 | 0.87 | CNR1 (0.46) | TBXAS1CNR1MAPTHDAC8HDAC1 | |
| SCHEMBL8843139 | 0.87 | CNR1 (0.46) | TBXAS1CNR1MAPTHDAC8HDAC1 | |
| SCHEMBL8652308 | 0.85 | AKR1C3 (0.37) | TBXAS1AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL8652312 | 0.85 | AKR1C3 (0.37) | TBXAS1AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL8654446 | 0.83 | BCHE (0.47) | TBXAS1CNR1 | |
| SCHEMBL8654502 | 0.83 | CNR1 (0.44) | CNR1HDAC8HDAC1ALDH1A1LMNA | |
| SCHEMBL9862579 | 0.76 | CNR1 (0.48) | PDE4BAKR1C3PTGS1FFAR1PPARG | |
| SCHEMBL7180072 | 0.76 | TBXAS1 (0.56) | TBXAS1PDE4BPTGS1FFAR1PPARG | |
| SCHEMBL7180064 | 0.76 | TBXAS1 (0.56) | TBXAS1PDE4BPTGS1FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585405-A | ADMINISTERING ANDROGEN OR ESTROGEN INHIBITORS | ENDORECHERCHE INC. (CA) | 1996-12-17 | — | — | US | disclosed |
| US-5364847-A | Inhibitors of sex steroid biosynthesis and methods for their production and use | ENDORECHERCHE (CA) | 1994-11-15 | — | — | US | disclosed |