Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | F7 | P08709 | 5/20 | 0.45 |
| ▸ | F3 | P13726 | 5/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452066 | 0.84 | CNR1 (0.62) | CNR1ALDH1A1 | |
| SCHEMBL9862463 | 0.82 | PDE4B (0.52) | PDE4BALDH1A1PPARGPPARDPPARA | |
| SCHEMBL11075357 | 0.78 | CYSLTR2 (0.44) | ALDH1A1F7F3CYP19A1PPARG | |
| SCHEMBL9230666 | 0.76 | TBXAS1 (0.51) | CNR1PDE4BALDH1A1PPARGPPARD | |
| SCHEMBL8673543 | 0.76 | TBXAS1 (0.51) | CNR1PDE4BALDH1A1PPARGPPARD | |
| SCHEMBL8843761 | 0.76 | CNR1 (0.60) | CNR1PDE4BFFAR1FFAR4 | |
| Oleic Acid SCHEMBL9757479 | 0.75 | PPARG (0.64) | CNR1ALDH1A1F7F3CYP19A1 | |
| Palmitoleic Acid SCHEMBL7828660 | 0.74 | CNR1 (0.65) | CNR1ALDH1A1F7F3CYP19A1 | |
| SCHEMBL8080134 | 0.74 | LTB4R (0.69) | CNR1PDE4BF3PPARGPPARD | |
| SCHEMBL1005790 | 0.74 | LTB4R (0.69) | CNR1PDE4BF3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021414-A | Antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0124369-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-24 | — | — | EP | disclosed |