⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293540 | 0.90 | TSHR (0.42) | — | |
| SCHEMBL1987431 | 0.83 | — | — | |
| SCHEMBL11823399 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL6017579 | 0.77 | TSHR (0.42) | — | |
| SCHEMBL9771895 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL605471 | 0.76 | — | — | |
| SCHEMBL1019318 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL9402757 | 0.76 | — | — | |
| SCHEMBL19512083 | 0.75 | HTT (0.52) | — | |
| SCHEMBL8728822 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704232-A1 | COMPOSITIONS AND METHODS FOR THE EXPANSION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-3703715-A1 | COMPOSITIONS AND METHODS FOR HEMATOPOIETIC STEM AND PROGENITOR CELL TRANSPLANT THERAPY | Magenta Therapeutics, Inc. (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-0684268-A1 | Low temperature curing agents for epoxy resins | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1995-11-29 | — | — | EP | disclosed |