Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929101 | 0.91 | TSHR (0.46) | TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL10969082 | 0.91 | TSHR (0.46) | TSHRLPAR3LPAR2LPAR1 | |
| SCHEMBL979514 | 0.87 | ALDH1A1 (0.45) | TSHRALDH1A1 | |
| SCHEMBL329204 | 0.86 | MEN1 (0.40) | TSHRALDH1A1LPAR3LPAR2LPAR1 | |
| SCHEMBL4394433 | 0.85 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL5163112 | 0.84 | — | — | |
| SCHEMBL11105491 | 0.84 | ALDH1A1 (0.43) | TSHRALDH1A1 | |
| SCHEMBL6344570 | 0.83 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL9470760 | 0.81 | HTT (0.50) | TSHRALDH1A1 | |
| SCHEMBL9469818 | 0.81 | HTT (0.50) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030040460-A1 | Use of thio derivatives as perfuming and flavoring ingredients | FIRMENICH SA (CH) | 2003-02-27 | — | — | US | claimed |
| EP-1249446-A2 | Use of thio derivates as perfuming and flavoring ingredients | FIRMENICH SA (CH) | 2002-10-16 | — | — | EP | claimed |
| US-7008919-B2 | Use of thio derivatives as perfuming and flavoring ingredients | FIRMENICH SA (CH) | 2006-03-07 | — | — | US | disclosed |
| US-20030040460-A1 | Use of thio derivatives as perfuming and flavoring ingredients | FIRMENICH SA (CH) | 2003-02-27 | — | — | US | disclosed |
| EP-1249446-A2 | Use of thio derivates as perfuming and flavoring ingredients | FIRMENICH SA (CH) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040460-A1 | Use of thio derivatives as perfuming and flavoring ingredients | TAS2R1, TAS2R4, TAS1R1 | TSHR 1235/4885ALDH1A1 166/4885LPAR3 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.