Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616719 | 0.77 | KDM4E (0.50) | SRCKDM4EL3MBTL1TSHRMEN1 | |
| SCHEMBL4614815 | 0.77 | MCL1 (0.45) | EGFRKDM4EL3MBTL1TSHRKMT2A | |
| SCHEMBL6363289 | 0.75 | EGFR (0.46) | EGFRSRCKDM4EL3MBTL1BRD1 | |
| SCHEMBL29858321 | 0.75 | EGFR (0.46) | EGFRSRCKDM4EL3MBTL1BRD1 | |
| SCHEMBL9956776 | 0.75 | KDM4E (0.52) | KDM4EL3MBTL1TSHRMEN1HPGD | |
| SCHEMBL16571464 | 0.74 | USP14 (0.36) | EGFRSRCF11L3MBTL1USP14 | |
| SCHEMBL16571637 | 0.74 | GPR35 (0.47) | EGFRSRCF11GRIA2GRIA4 | |
| SCHEMBL4615149 | 0.73 | SRC (0.47) | SRCKDM4EL3MBTL1TSHRMEN1 | |
| SCHEMBL8367878 | 0.73 | EGFR (0.45) | EGFRSRCKDM4EUSP14BRD1 | |
| SCHEMBL30639179 | 0.73 | KDM4E (0.67) | EGFRKDM4EL3MBTL1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655439-A2 | 5,6-Bicyclic glycoprotein IIb IIIa antagonists useful in inhibition of platelet aggregation | ELI LILLY AND COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |