Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 8/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456162 | 0.89 | MAPK1 (0.44) | PNPHPRT1KMT2AMEN1MAPK1 | |
| SCHEMBL6046932 | 0.88 | PNP (0.42) | PNPHPRT1KMT2AMEN1MAPK1 | |
| SCHEMBL453174 | 0.87 | PNP (0.49) | PNPHPRT1TLR7KMT2AMEN1 | |
| SCHEMBL6046944 | 0.70 | KDM4E (0.33) | PNPMAPK1ALDH1A1 | |
| SCHEMBL23921107 | 0.68 | PNP (0.47) | PNPHPRT1MAPK1HBBALDH1A1 | |
| SCHEMBL4813936 | 0.67 | PNP (0.70) | PNPTLR7KMT2AMEN1ALDH1A1 | |
| SCHEMBL21977325 | 0.67 | PNP (0.51) | PNPALDH1A1SMN1; SMN2 | |
| SCHEMBL23921134 | 0.67 | PNP (0.46) | PNPHPRT1KMT2AMEN1MAPK1 | |
| SCHEMBL9566544 | 0.67 | PNP (0.71) | PNPHPRT1KMT2AMEN1MAPK1 | |
| SCHEMBL7200361 | 0.67 | PNP (0.46) | PNPHPRT1KMT2AMEN1HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672661-A1 | Substituted N-ethyl-glycinderivatives for the preparation of PNA and PNA-/DNA hybrides | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |