SCHEMBL923219

SCHEMBL923219

CCOc1cccc(CNC(=O)c2cccnc2N)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.67
KMT2A Q03164 2/20 0.67
ROCK1 Q13464 3/20 0.59
CYP3A4 P08684 3/20 0.59
CYP2D6 P10635 3/20 0.59
ROCK2 O75116 2/20 0.59
CYP2C9 P11712 2/20 0.59
ALDH1A1 P00352 3/20 0.56
KDM4E B2RXH2 2/20 0.56
USP2 O75604 1/20 0.56
THRB P10828 1/20 0.54
CYP1A2 P05177 1/20 0.53
CYP2C19 P33261 1/20 0.53
LMNA P02545 3/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
KLKB1 P03952 1/20 0.53
KLK1 P06870 1/20 0.53
MAPK8 P45983 1/20 0.51
MEN1 O00255 1/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920709 0.96 HPGD (0.62) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL919694 0.92 HPGD (0.61) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL921059 0.91 ROCK1 (0.61) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL920791 0.90 HPGD (0.58) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL923068 0.89 HPGD (0.72) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL920921 0.89 HPGD (0.58) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL921824 0.89 HPGD (0.58) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL921958 0.89 HPGD (0.57) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL920646 0.89 HPGD (0.59) HPGDKMT2AROCK1CYP3A4CYP2D6
SCHEMBL919731 0.88 HPGD (0.59) HPGDKMT2AROCK1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885KMT2A 2469/4885ROCK1 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.