Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232195 | 1.00 | POLB (0.35) | POLBTPSAB1TPSD1TPSG1HTT | |
| Hydrochloric Acid SCHEMBL9232673 | 0.89 | POLB (0.38) | POLBTPSAB1TPSD1TPSG1HTT | |
| SCHEMBL9232725 | 0.83 | POLB (0.35) | POLBTPSAB1TPSD1TPSG1HTT | |
| SCHEMBL9232731 | 0.83 | POLB (0.35) | POLBTPSAB1TPSD1TPSG1HTT | |
| Bicarbonate SCHEMBL9235058 | 0.83 | HTT (0.49) | POLBTPSAB1TPSD1TPSG1HTT | |
| SCHEMBL9235050 | 0.82 | POLB (0.38) | POLBTPSAB1TPSD1TPSG1HTT | |
| Bicarbonate SCHEMBL9239312 | 0.78 | HTT (0.49) | POLBHTTEPHX2PKMTSHR | |
| SCHEMBL9237480 | 0.78 | ITGB3 (0.41) | POLBITGB3ITGA2BTLR9TLR8 | |
| SCHEMBL9237479 | 0.78 | ITGB3 (0.41) | POLBITGB3ITGA2BTLR9TLR8 | |
| Hydrochloric Acid SCHEMBL9235766 | 0.78 | POLB (0.36) | POLBTPSAB1TPSD1TPSG1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | claimed |
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |