Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237480 | 1.00 | ITGB3 (0.41) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9235576 | 0.91 | ITGB3 (0.38) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL9232731 | 0.82 | POLB (0.35) | POLBTLR9TLR8TLR7 | |
| SCHEMBL9232725 | 0.82 | POLB (0.35) | POLBTLR9TLR8TLR7 | |
| SCHEMBL9236133 | 0.79 | GPR119 (0.41) | RBP4EPHX1 | |
| SCHEMBL9232195 | 0.78 | POLB (0.35) | ITGB3ITGA2BPOLBTLR9TLR8 | |
| SCHEMBL9232196 | 0.78 | POLB (0.35) | ITGB3ITGA2BPOLBTLR9TLR8 | |
| Hydrochloric Acid SCHEMBL9235766 | 0.75 | POLB (0.36) | POLBTLR9TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL9235762 | 0.75 | ITGB3 (0.38) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Bicarbonate SCHEMBL9235058 | 0.74 | HTT (0.49) | POLBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |