Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004668 | 0.85 | RAB9A (0.57) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL9004741 | 0.84 | MAPT (0.53) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL9004654 | 0.82 | KMT2A (0.51) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL9004618 | 0.82 | KMT2A (0.63) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL9004650 | 0.82 | MAPT (0.51) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL9227706 | 0.79 | MAPT (0.51) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL9004683 | 0.79 | SENP6 (0.56) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL9004655 | 0.79 | KMT2A (0.57) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL8667830 | 0.78 | SENP6 (0.61) | SENP6CASP3SENP8SENP7MAPT | |
| SCHEMBL9004783 | 0.78 | RAB9A (0.55) | SENP6CASP3SENP8SENP7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |