Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530751 | 0.81 | CYP19A1 (0.52) | PKMMAPTNPC1RAB9A | |
| SCHEMBL12620351 | 0.75 | FLT3 (0.54) | FLT3GSK3BTP53PKMLMNA | |
| SCHEMBL11591093 | 0.73 | FLT3 (0.77) | FLT3GSK3BMMP2 | |
| SCHEMBL25983329 | 0.68 | HDAC3 (0.51) | FLT3GSK3BHDAC3HDAC4HDAC1 | |
| SCHEMBL1456921 | 0.66 | LMNA (0.59) | FLT3GSK3BTP53PKMLMNA | |
| SCHEMBL16271178 | 0.66 | FLT3 (0.66) | FLT3GSK3B | |
| SCHEMBL9141194 | 0.65 | — | — | |
| SCHEMBL28795624 | 0.65 | MAPT (0.92) | TP53PKMLMNAMAPTHDAC1 | |
| SCHEMBL21111108 | 0.64 | KMT2A (0.62) | TP53LMNAMAPTNPC1RAB9A | |
| SCHEMBL9728 | 0.61 | MAPT (1.00) | TP53PKMLMNAMAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641797-A1 | Cephem derivatives and antimicrobial agents containing the same | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |