Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233526 | 0.81 | FLT3 (0.50) | MAPTPKMNPC1RAB9A | |
| SCHEMBL16090317 | 0.74 | CYP19A1 (0.52) | CYP19A1BCHEALDH1A1PTGS2CA12 | |
| SCHEMBL28316960 | 0.74 | CYP19A1 (0.52) | CYP19A1BCHEKDM4EALDH1A1MAPT | |
| SCHEMBL6728354 | 0.74 | CYP19A1 (0.52) | CYP19A1BCHEKDM4EALDH1A1MAPT | |
| SCHEMBL5326554 | 0.74 | CYP19A1 (0.52) | CYP19A1BCHEALDH1A1PTGS2CA12 | |
| SCHEMBL16754127 | 0.74 | CYP19A1 (0.52) | CYP19A1BCHEALDH1A1PTGS2CA12 | |
| SCHEMBL2687071 | 0.74 | KMT2A (0.52) | CYP19A1BCHEPTGS2CA12CA1 | |
| SCHEMBL15108602 | 0.74 | CYP19A1 (0.66) | CYP19A1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL16206235 | 0.72 | CYP19A1 (0.70) | CYP19A1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL1119554 | 0.72 | PTGS2 (0.66) | CYP19A1BCHEPTGS2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322359-B1 | ISOINDOLINE PIGMENTS CONTAINING AT LEAST A TRIAZOLOPYRIMIDONE REST | CIBA-GEIGY AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| EP-0322359-A2 | Isoindoline pigments containing at least a triazolopyrimidone rest | CIBA-GEIGY AG (CH) | 1989-06-28 | — | — | EP | disclosed |
| US-4000135-A | IRON TETRAAZANNULENES AS CATALYSTS | BASF AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |