Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466929 | 0.96 | LMNA (0.68) | LMNACA2CA12CA1CA4 | |
| SCHEMBL311488 | 0.96 | LMNA (0.68) | LMNACA2CA12CA1CA4 | |
| SCHEMBL8802752 | 0.96 | LMNA (0.68) | LMNACA2CA12CA1CA4 | |
| SCHEMBL28717130 | 0.91 | MAOB (0.65) | LMNACA2CA12CA1CA4 | |
| SCHEMBL29466930 | 0.87 | ALDH1A1 (0.66) | LMNAMAOBALDH1A1TDP1TSHR | |
| SCHEMBL10491259 | 0.87 | ALDH1A1 (0.66) | LMNAMAOBALDH1A1TDP1TSHR | |
| SCHEMBL9155427 | 0.87 | LMNA (0.71) | LMNACA2CA12CA1CA4 | |
| SCHEMBL139680 | 0.87 | ALDH1A1 (0.66) | LMNAMAOBALDH1A1TDP1TSHR | |
| SCHEMBL1305704 | 0.87 | ALDH1A1 (0.56) | LMNAMAOBALDH1A1TDP1TSHR | |
| SCHEMBL34546 | 0.86 | LMNA (1.00) | LMNACA2CA12CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553612-B1 | Polyimides, thermosetting resin compositions containing the polyimides, formed articles of the resin compositions, and production process of the polyimides | HITACHI CHEMICAL CO LTD (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5510425-A | AROMATIC POLYIMIDE-EPOXY COPOLYMER MODIFIED BY BISMALEIMIDE COMPOUND; FLEXIBILITY, PEELING STRENGTH; COLDSETTING RESINS, ADHESIVES | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5508357-A | SOLUBILITY IN SOLVENT, LOW MELTING POINT | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0553612-A2 | Polyimides, thermosetting resin compositions containing the polyimides, formed articles of the resin compositions, and production process of the polyimides | HITACHI CHEMICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |