Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Cyclohexane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL98192 | 0.90 | TSHR (0.43) | TSHRLMNATHRBANPEP | |
| Hydrochloric Acid SCHEMBL18528453 | 0.84 | TSHR (0.38) | TSHRLMNATHRBANPEP | |
| Hydrogen Sulfide SCHEMBL9252049 | 0.83 | TSHR (0.43) | TSHRLMNATHRBANPEP | |
| SCHEMBL6121770 | 0.83 | TSHR (0.43) | TSHRLMNATHRBANPEP | |
| Fluoride Ion SCHEMBL839652 | 0.83 | TSHR (0.43) | TSHRLMNATHRBANPEP | |
| SCHEMBL15122 | 0.83 | TSHR (0.43) | TSHRLMNATHRBANPEP | |
| SCHEMBL152801 | 0.83 | TSHR (0.43) | TSHRLMNATHRBANPEP | |
| Iodide SCHEMBL1172044 | 0.83 | TSHR (0.43) | TSHRLMNATHRBANPEP | |
| Water SCHEMBL439121 | 0.83 | TSHR (0.43) | TSHRLMNATHRBANPEP | |
| Bromide SCHEMBL154033 | 0.83 | TSHR (0.43) | TSHRLMNATHRBANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484872-A | LENSES, FILTERS | DAISO CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |