Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.39 |
| ▸ | F2R | P25116 | 7/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9237559 | 0.91 | POLB (0.41) | POLBITGB3ITGA2BF2RCHRNB2 | |
| Hydrochloric Acid SCHEMBL9238344 | 0.83 | ITGB3 (0.49) | POLBITGB3ITGA2BF2RCHRNB2 | |
| SCHEMBL9236151 | 0.80 | HPGD (0.53) | EPHX2 | |
| Hydrochloric Acid SCHEMBL9234386 | 0.77 | POLB (0.50) | POLBITGB3ITGA2BF2RCHRNB2 | |
| Hydrochloric Acid SCHEMBL9409489 | 0.75 | POLB (0.43) | POLBITGB3ITGA2BF2R | |
| Hydrochloric Acid SCHEMBL9239409 | 0.72 | CHRNB2 (0.41) | POLBITGB3ITGA2BCHRNB2CHRNA3 | |
| Hydrochloric Acid SCHEMBL9237247 | 0.71 | CHRNB2 (0.47) | ITGB3ITGA2BF2RCHRNB2CHRNA3 | |
| Trifluoroacetic Acid SCHEMBL3961122 | 0.71 | HTT (0.51) | ITGB3ITGA2BCHRNB2CHRNA3CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL1437588 | 0.70 | POLB (0.61) | POLBEPHX2 | |
| SCHEMBL9231469 | 0.70 | HPGD (0.54) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |