SCHEMBL9236559

SCHEMBL9236559

CC(SC(=O)OC(C)(C)C)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
EPHX1 P07099 2/20 0.32
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
DGAT1 O75907 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28872836 0.74 CA1 (0.32) CA12CA14CA1CA2CA7
SCHEMBL20657366 0.73 CA1 (0.31) NOS1NOS3NOS2CA1CA2
SCHEMBL11875307 0.72 KMT2A (0.34) NOS1NOS3NOS2CA1CA2
SCHEMBL21929526 0.69
SCHEMBL25764373 0.67
SCHEMBL27471646 0.67
SCHEMBL29708406 0.66 DGAT1 (0.40) CA1CA2CA7DGAT1
Isopropyl Alcohol SCHEMBL27636953 0.66 NOS1 (0.38) NOS1NOS3NOS2CA12CA14
SCHEMBL3073411 0.66
SCHEMBL4376025 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641769-A1 AMINO ACID DERIVATIVE SANKYO COMPANY LIMITED (JP) 1995-03-08 EP disclosed