Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142680 | 0.97 | OPRM1 (0.40) | OPRM1CA2CA1ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL4336850 | 0.95 | OPRM1 (0.39) | OPRM1CA2CA1ALDH1A1TDP1 | |
| Water SCHEMBL11611074 | 0.95 | OPRM1 (0.39) | OPRM1CA2CA1ALDH1A1TDP1 | |
| Bromide SCHEMBL28453702 | 0.93 | OPRM1 (0.48) | OPRM1CA1DNM1SLC1A2SLC1A1 | |
| Bromide SCHEMBL923753 | 0.91 | OPRM1 (0.46) | OPRM1CA2DNM1TSHRSPHK1 | |
| Bromide SCHEMBL5088250 | 0.91 | OPRM1 (0.46) | OPRM1CA2DNM1TSHRSPHK1 | |
| Bromide SCHEMBL139792 | 0.91 | OPRM1 (0.46) | OPRM1CA2DNM1TSHRSPHK1 | |
| Bromide SCHEMBL475827 | 0.91 | OPRM1 (0.46) | OPRM1CA2DNM1TSHRSPHK1 | |
| Bromide SCHEMBL489783 | 0.91 | OPRM1 (0.46) | OPRM1CA2DNM1TSHRSPHK1 | |
| Bromide SCHEMBL923748 | 0.91 | OPRM1 (0.46) | OPRM1CA2DNM1TSHRSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230831-B | Preparation method of cross-linked anion exchange membrane with high oxidation stability and high ion conductivity | 福州大学 | 2023-06-09 | — | — | CN | claimed |
| CN-114133555-B | Preparation method of cross-linked fluorine-containing polyfluorene ether anion exchange membrane | 福州大学 | 2023-05-16 | — | — | CN | claimed |
| CN-114230831-A | Preparation method of cross-linked anion exchange membrane with high oxidation stability and high ionic conductivity | 福州大学 | 2022-03-25 | — | — | CN | claimed |
| CN-114133555-A | Preparation method of cross-linked fluorine-containing polyfluorene ether anion exchange membrane | 福州大学 | 2022-03-04 | — | — | CN | claimed |
| CN-117343305-A | Tri-center Schiff base catalyst and preparation method thereof and preparation method of polyglycolide | 中国科学院长春应用化学研究所 | 2024-01-05 | — | — | CN | disclosed |
| CN-114230831-B | Preparation method of cross-linked anion exchange membrane with high oxidation stability and high ion conductivity | 福州大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-114133555-B | Preparation method of cross-linked fluorine-containing polyfluorene ether anion exchange membrane | 福州大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-114133555-B | Preparation method of cross-linked fluorine-containing polyfluorene ether anion exchange membrane | 福州大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-114230831-A | Preparation method of cross-linked anion exchange membrane with high oxidation stability and high ionic conductivity | 福州大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-114133555-A | Preparation method of cross-linked fluorine-containing polyfluorene ether anion exchange membrane | 福州大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-114133555-A | Preparation method of cross-linked fluorine-containing polyfluorene ether anion exchange membrane | 福州大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-107840347-B | Titanium-silicon molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| EP-2738165-B1 | Method by means of phase transfer catalysis | WÖRWAG PHARMA GMBH & CO KG (DE) | 2016-10-12 | — | — | EP | disclosed |
| EP-2738165-A1 | Method by means of phase transfer catalysis | WÖRWAG PHARMA GmbH & Co. KG (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-8415059-B2 | Direct electron transfer using enzymes in bioanodes, biocathodes, and biofuel cells | ST. LOUIS UNIVERSITY (US) | 2013-04-09 | — | — | US | disclosed |
| US-20110014549-A9 | DIRECT ELECTRON TRANSFER USING ENZYMES IN BIOANODES, BIOCATHODES, AND BIOFUEL CELLS | ST. LOUIS UNIVERSITY (US) | 2011-01-20 | — | — | US | disclosed |
| US-20090305113-A1 | DIRECT ELECTRON TRANSFER USING ENZYMES IN BIOANODES, BIOCATHODES, AND BIOFUEL CELLS | ST. LOUIS UNIVERSITY (US) | 2009-12-10 | — | — | US | disclosed |
| EP-1952469-A2 | DIRECT ELECTRON TRANSFER USING ENZYMES IN BIOANODES, BIOCATHODES, AND BIOFUEL CELLS | ST. LOUIS UNIVERSITY (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007084249-A2 | DIRECT ELECTRON TRANSFER USING ENZYMES IN BIOANODES, BIOCATHODES, AND BIOFUEL CELLS | ST.LOUIS UNIVERSITY (US) | 2007-07-26 | — | — | WO | disclosed |
| WO-2005094806-A1 | USE OF QUATERNARY AMMONIUM COMPOUNDS AS SPECIFIC BLOCKERS OF TRANSPORT THROUGH AQUAPORIN, COMPOSITIONS COMPRISING THE COMPOUNDS AND METHOD OF SELECTING THE COMPOUNDS | STICHTING KATHOLIEKE UNIVERSITEIT (NL) | 2005-10-13 | — | — | WO | disclosed |