Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238806 | 1.00 | PPARG (0.50) | PPARGPPARAFFAR1SLC1A3SLC1A2 | |
| SCHEMBL9241636 | 0.82 | KMT2A (0.44) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9241640 | 0.82 | KMT2A (0.44) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9237163 | 0.81 | SMN1; SMN2 (0.43) | SLC1A2KIF11 | |
| SCHEMBL9237158 | 0.81 | SMN1; SMN2 (0.43) | SLC1A2KIF11 | |
| SCHEMBL9236830 | 0.81 | PPARG (0.43) | PPARGPPARAFFAR1SLC1A3SLC1A2 | |
| SCHEMBL9241984 | 0.81 | PPARG (0.47) | PPARGPPARAFFAR1SLC1A3SLC1A2 | |
| SCHEMBL9236828 | 0.81 | PPARG (0.43) | PPARGPPARAFFAR1SLC1A3SLC1A2 | |
| SCHEMBL9237136 | 0.79 | CYP1A2 (0.51) | PPARGPPARAFFAR1SLC1A3SLC1A2 | |
| SCHEMBL9238852 | 0.79 | PPARG (0.50) | PPARGPPARAFFAR1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658539-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1995-06-21 | — | — | EP | disclosed |