SCHEMBL9237225

CC(C)[C@H](NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.63

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	16/20	0.63

▸	GLP1R	P43220	2/20	0.59

▸	NPBWR1	P48145	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9237145	1.00	IL23R (0.63)	IL23RGLP1RNPBWR1
SCHEMBL8973385	0.95	IL23R (0.64)	IL23RGLP1R
SCHEMBL31664375	0.89	GLP1R (0.68)	IL23RGLP1R
SCHEMBL31664363	0.89	GLP1R (0.67)	GLP1R
SCHEMBL31664372	0.88	GLP1R (0.69)	GLP1R
SCHEMBL29641072	0.88	GLP1R (0.65)	IL23RGLP1R
SCHEMBL12417449	0.87	KISS1R (0.61)	IL23R
SCHEMBL29936309	0.87	GLP1R (0.65)	GLP1R
SCHEMBL30587681	0.86	GLP1R (0.72)	GLP1R
SCHEMBL30823856	0.85	GLP1R (0.76)	GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1995026744-A1	TUMOR NECROSIS FACTOR INHIBITORS	CENTOCOR, INC. (US)	1995-10-12	—	—	WO	disclosed