SCHEMBL29641072

SCHEMBL29641072

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)[C@@H](C)O)C(C)C)C(=O)N[C@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 16/20 0.65
▸ IL23R Q5VWK5 4/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29936309 0.97 GLP1R (0.65) GLP1R
SCHEMBL31688323 0.89 GLP1R (0.66) GLP1R
SCHEMBL20816299 0.89 GLP1R (0.80) GLP1R
SCHEMBL30587681 0.89 GLP1R (0.72) GLP1R
SCHEMBL30592733 0.89 GLP1R (0.55) GLP1RIL23R
SCHEMBL30216755 0.88 GLP1R (0.72) GLP1RIL23R
SCHEMBL9237145 0.88 IL23R (0.63) GLP1RIL23R
SCHEMBL9237225 0.88 IL23R (0.63) GLP1RIL23R
SCHEMBL31072729 0.88 GLP1R (0.81) GLP1R
SCHEMBL30451312 0.88 C5AR1 (0.70) GLP1RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711005-A2 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH Stealth BioTherapeutics Inc. (US) 2026-03-18 — — EP disclosed
US-20250263433-A1 METHODS FOR REDUCING CD36 EXPRESSION CORNELL RESEARCH FOUNDATION, INC. (US) 2025-08-21 — — US disclosed
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 — — EP disclosed
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2025-05-22 — — US disclosed
EP-4302829-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2025-05-21 — — EP disclosed
EP-3603658-B1 PEPTIDE FOR USE IN THE TREATMENT OF HEART FAILURE RESULTING FROM HYPERTROPHIC CARDIOMYOPATHY UNIV CORNELL (US) 2025-01-08 — — EP disclosed
US-12102659-B2 Methods for the prevention or treatment of heart failure CORNELL UNIVERSITY (US) 2024-10-01 — — US disclosed
US-11998585-B2 Methods and compositions for increasing the dose of a chemotherapeutic agent STEALTH BIOTHERAPEUTICS INC. (US) 2024-06-04 — — US disclosed
US-11944662-B2 Methods and compositions for preventing or treating ophthalmic conditions STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-02 — — US disclosed
EP-4285994-A2 METHODS FOR THE PREVENTION OR TREATMENT OF NO-REFLOW FOLLOWING ISCHEMIA/REPERFUSION INJURY Stealth BioTherapeutics Inc. (US) 2023-12-06 — — EP disclosed
US-20230285499-A1 METHODS FOR THE PREVENTION OR TREATMENT OF HEART FAILURE CORNELL UNIVERSITY (US) 2023-09-14 — — US disclosed
EP-4233887-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2023-08-30 — — EP disclosed
US-20230149501-A1 METHODS FOR REDUCING OXIDATIVE DAMAGE CORNELL RESEARCH FOUNDATION, INC. (US) 2023-05-18 — — US disclosed
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-06 — — US disclosed
EP-3513800-B1 AROMATIC-CATIONIC PEPTIDE FOR USE IN THE TREATMENT OF ANTIPHOSPHOLIPID SYNDROME UNIV CORNELL (US) 2022-12-07 — — EP disclosed
EP-4085920-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2022-11-09 — — EP disclosed
US-11376304-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2022-07-05 — — US disclosed
US-11366104-B2 Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening STEALTH BIOTHERAPEUTICS INC. (US) 2022-06-21 — — US disclosed
EP-4005582-A1 TREATMENT OF LEFT VENTRICULAR REMODELING Stealth BioTherapeutics Inc. (US) 2022-06-01 — — EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285499-A1 METHODS FOR THE PREVENTION OR TREATMENT OF HEART FAILURE TNNI3, FABP3, TNNC1 GLP1R 142/4885IL23R 4061/4885
US-11944662-B2 Methods and compositions for preventing or treating ophthalmic conditions CRYAA, CRYAB, IAPP GLP1R 34/4885IL23R 3422/4885
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 GLP1R 2360/4885IL23R 4208/4885
US-12102659-B2 Methods for the prevention or treatment of heart failure TNNI3, FABP3, TNNC1 GLP1R 142/4885IL23R 4061/4885
US-11998585-B2 Methods and compositions for increasing the dose of a chemotherapeutic agent OPRL1, TSG101, NGF GLP1R 1187/4885IL23R 2694/4885
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 GLP1R 2360/4885IL23R 4208/4885
US-11376304-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 GLP1R 1920/4885IL23R 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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