Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600315 | 0.84 | FAAH (1.00) | FAAHKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL9238946 | 0.84 | POLB (0.53) | FAAHPOLBNAMPT | |
| SCHEMBL7238932 | 0.84 | POLB (0.68) | FAAHKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL10719972 | 0.83 | HTT (0.78) | KMT2AMEN1SMN1; SMN2HTTCA12 | |
| SCHEMBL7233426 | 0.81 | HTT (0.62) | FAAHKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL7248523 | 0.81 | FAAH (0.82) | FAAHKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL13234936 | 0.81 | FAAH (0.82) | FAAHKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL3598122 | 0.81 | FAAH (1.00) | FAAHKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL7232379 | 0.80 | HTT (0.73) | KMT2AMEN1HTTCA12CA1 | |
| SCHEMBL10762328 | 0.79 | ACHE (0.63) | KMT2AMEN1HTTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |