Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237953 | 0.95 | DHODH (0.44) | DHFRCYP4F2CYP4A11DHODHPARP1 | |
| SCHEMBL9236783 | 0.95 | DHFR (0.48) | DHFRCYP4F2CYP4A11DHODHPARP1 | |
| SCHEMBL9236494 | 0.95 | DHFR (0.52) | DHFRCYP4F2CYP4A11DHODHPARP1 | |
| SCHEMBL9235293 | 0.89 | DHODH (0.46) | DHFRCYP4F2CYP4A11DHODHPARP1 | |
| SCHEMBL9231896 | 0.89 | DHODH (0.46) | DHFRCYP4F2CYP4A11DHODHPARP1 | |
| SCHEMBL9235705 | 0.87 | DHFR (0.55) | DHFRCYP4F2CYP4A11DHODHPARP1 | |
| SCHEMBL9233264 | 0.83 | DHODH (0.47) | DHFRCYP4F2CYP4A11DHODHPARP1 | |
| SCHEMBL9238060 | 0.82 | DHODH (0.48) | DHFRCYP4F2CYP4A11DHODHPARP1 | |
| SCHEMBL9237047 | 0.81 | DHFR (0.53) | DHFRCYP4F2CYP4A11DHODHLOXL2 | |
| SCHEMBL9233991 | 0.81 | DHFR (0.48) | DHFRCYP4F2CYP4A11DHODHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685467-A1 | NOVEL PYRIMIDINE DERIVATIVE AND MEDICINAL COMPOSITION | NKK CORPORATION (JP) | 1995-12-06 | — | — | EP | disclosed |